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糖尿病肾病时具有血浆、肾脏局部及尿液内皮素 (ET)含量变化。ET通过干扰正常血糖代谢、影响体内其他细胞因子与生长因子以及改变肾脏血流动力、调节水盐代谢等机理参与糖尿病肾病的发生与进展。
Diabetic nephropathy with plasma, renal local and urinary endothelin (ET) content changes. ET participates in the occurrence and progression of diabetic nephropathy by interfering with normal blood glucose metabolism, affecting other cytokines and growth factors in the body, changing renal hemodynamics and regulating water and salt metabolism.