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目的对呼吸内科抗生素的合理应用及药学干预方法进行分析,为科学用药提供参考。方法选取医院2014年1月-2014年12月呼吸内科未派驻临床药师的时间段为对照期,选取医院2015年1月-2015年12月呼吸内科派驻临床药师的时间段为观察期,各随机抽取100例患者为观察对象,分析抗生素的使用强度、合理性、不良反应、成本效益。结果与对照期比较,观察期抗生素使用强度、联用率、使用合理率、不良反应发生率、平均住院时间、抗生素疗程、抗生素费用均较优,差异有统计学意义(P<0.05)。结论有效的药学干预对呼吸内科抗生素的合理应用具有促进作用,应推广应用。
Objective To analyze the rational use of antibiotics in respiratory medicine and the methods of pharmaceutical intervention, and provide reference for scientific medication. Methods The time period from January 2014 to December 2014 in which no clinical pharmacist was stationed in the department of respiratory medicine in the hospital from January 2014 to December 2014 was selected as the control period. The time period from January 2015 to December 2015 in which the clinical pharmacist was stationed in the Department of Respiratory Medicine was selected as the observation period 100 patients were selected as the observation object, analysis of the use of antibiotics, rationality, adverse reactions, cost-effectiveness. Results Compared with the control period, the antibiotic use intensity, combination rate, rational use rate, adverse reaction rate, average length of stay, duration of antibiotic treatment and antibiotic expense in the observation period were all excellent. The difference was statistically significant (P <0.05). Conclusion Effective pharmacological interventions can promote the rational use of antibiotics in respiratory medicine and should be widely applied.