编者按卒中不仅仅损伤神经元,更重要的是对神经血管单元和与此相关的微环境造成破坏,损伤细胞功能和细胞之间的信号传递。以往相关的科研只注重单一的神经元保护研究,现在越来越重视神经血管单元功能的修复和重塑以恢复神经功能的研究。目前,实验性卒中干预方法较多,如应用药物小分子、基因、干细胞以及基于基因的干细胞治疗等,其主要目的是通过促进卒中后神经再生和血管新生以修复 Editor’s note, stroke not only damages neurons, but more importantly, damage to neurovascular units and the microenvironment associated with them, impairing cellular function and signaling between cells. In the past, related research focused on single neuron protection research, and now more and more attention is paid to the repair and remodeling of the function of neurovascular units to restore neurological function. At present, there are more experimental stroke interventions, such as the use of small drug molecules, genes, stem cells and gene-based stem cell therapy, etc. The main purpose is to repair post-stroke nerve regeneration and angiogenesis