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对55例脑梗死患者分别于发病后1天、3天、1周、2周、1月时检测血浆D-二聚体（D-D）水平及纤溶酶原（PLG）活性，同时检查记录神经功能缺损评分。结果显示:与43例正常对照组比较，患者组纤溶活性显著增强，D-D水平于3天时达高峰（P＜0.001），与同期明显降低的PLG活性（P＜0.001）呈负相关（r—-0.446，P＜0.001）。D-D水平于1月时仍高于正常（P＜0.01）。脑梗死早期纤溶活性与神经功能缺损评分呈显著性正相关（P＜0.01）。腔隙性梗死组纤溶活性亦有显著性增强，其变化规律与皮层梗死组一致，但程度较低（P＜0.05）。
The levels of plasma D-dimer (DD) and plasminogen activator (PLG) were measured in 55 patients with cerebral infarction at 1 day, 3 days, 1 week, 2 weeks and 1 month after onset of symptoms. Functional impairment score. The results showed that compared with 43 normal controls, the fibrinolytic activity was significantly increased in patients with DD level (P <0.001) at 3 days and negatively correlated with significantly decreased PLG activity (P <0.001) -0.446, P <0.001). D-D levels remained above normal at 1 month (P <0.01). The early stage of cerebral infarction fibrinolytic activity and neurological deficit score was significantly positive correlation (P <0.01). The fibrinolytic activity of lacunar infarction group also significantly increased, the change rule consistent with the cortical infarction group, but to a lesser extent (P <0.05).