研究表明:中脑黑质多巴胺能神经元变性缺失伴胞浆内Lewy小体的形成是帕金森病的主要病理改变。近年来,大量的实验证实:中药在体外可诱导MSCs分化为神经前体细胞及神经元。倘若我们可通过中药激活内源性的MSCs不断向脑内迁移,进而分化为DA能神经元,那么,相对于神经干细胞移植术而言,该治疗手段将有可能显得更为简单、安全。 Studies have shown that: the degeneration of dopaminergic neurons in the substantia nigra with the formation of cytoplasmic Lewy bodies is the main pathological change of Parkinson’s disease. In recent years, a large number of experiments confirmed: Chinese medicine can induce MSCs differentiate into neural precursor cells and neurons in vitro. If we can activate endogenous MSCs through traditional Chinese medicine to migrate to the brain and then differentiate into DA neurons, then this treatment will probably be easier and safer than neural stem cell transplantation.