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庚型肝炎病毒(HGV)与散发性肝炎、暴发型肝炎及输血后肝炎有关,但尚未获得其传播的分子学证据。本文报道了2例由序列分析证实的经输血传播的庚型肝炎。 例1,男,56岁,患有严重再生障碍性贫血;例2,女,40岁,患有丙型肝炎和晚期肝硬变。用RT-PCR检测,发现例1的第一份血清和数份随访血清为HGV RNA阳性;例2在肝移植术前的3份血清为HGV RNA阴性,而肝移植后的所有血清样本均为阳性。例1曾接受3名供血者的血液,例2在第一次
Hepatitis G virus (HGV) is associated with sporadic hepatitis, fulminant hepatitis and post-transhepatic hepatitis, but no molecular evidence of its spread has yet been obtained. This article reports 2 transfusion-confirmed hepatitis G confirmed by sequence analysis. Example 1, male, 56 years old with severe aplastic anemia; case 2, female, 40 years old with hepatitis C and advanced liver cirrhosis. The first serum of Example 1 and several follow-up sera were found to be positive for HGV RNA by RT-PCR. Example 2 Three serums prior to liver transplantation were negative for HGV RNA and all serum samples after liver transplantation were Positive. Example 1 received blood from 3 donors, Example 2 for the first time