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为了探索骨髓增生异常综合征(MDS)的演变及转化规律,我们对24例MDS转化成急性白血病(AL)者(MDS-AL)进行了对照研究。 临床资料:男10例,女14例;年龄18～63岁。病程15天～3个月。从MDS转化成AL间隔时间13～270天,平均83天。MDS类型:Ⅱ型13例,Ⅴ型11例。转化成AL类型均为急非淋。其中M_(2a)12例,M_(5b)8例,M_(2b)、M4、低增生性白血病、未定型各1例。对照组:AL组20例系随机抽样。男10例,女10例,年龄18～67岁,病程3～90天,AL类型:ALL3例,M2b5例,M2b3例,M_35例,M_42例,M_52例。
In order to explore the evolution and transformation of myelodysplastic syndromes (MDS), we conducted a controlled study of 24 patients with MDS-transformed acute leukemia (MDS-AL). Clinical data: 10 males and 14 females; aged 18 to 63 years. Duration of 15 days to 3 months. Conversion from MDS to AL interval 13 to 270 days, an average of 83 days. MDS type: 13 cases of type Ⅱ, 11 cases of type Ⅴ. Conversion into AL types are urgent Fei Lin. There were 12 cases of M_ (2a), 8 cases of M_ (5b), M_ (2b), M4, low proliferative leukemia. Control group: AL group of 20 cases were randomly selected. 10 males and 10 females, aged 18 to 67 years, duration of 3 to 90 days, AL type: ALL3 cases, M2b5 cases, M2b3 cases, M35 cases, M42 cases, M52 cases.