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成纤维细胞生长因子（ＦＧＦｓ）是存在于生物体内的一组活性多肽，其中碱性ＦＧＦ（ｂＦＧＦ）为肝素亲和性生长因子。近年来研究表明，ｂＦＧＦ在人甲状腺组织增生、肿瘤，特别是甲状腺癌发病过程中具有重要作用。甲状腺组织中ｂＦＧＦ分子量大小、组织学定位及其含量高低与甲状腺癌的恶性度和淋巴转移状况有密切关系。
Fibroblast growth factors (FGFs) are a group of active polypeptides that are present in an organism, where basic FGF (bFGF) is a heparin affinity growth factor. Recent studies have shown that bFGF plays an important role in the development of human thyroid tissue proliferation, tumors, and especially thyroid cancer. The molecular weight, histological location and content of bFGF in thyroid tissue are closely related to the degree of malignancy and lymphatic metastasis of thyroid cancer.