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目的探讨中西医结合治疗2型糖尿病临床疗效分析及不良反应。方法将104例2型糖尿病患者随机分为二组,分别为对照组和观察组,各52例。对照组采用西药治疗,观察组在对照组基础上加用中药治疗。疗程均为12周,观察二组患者疗效,治疗前后FPG、餐后2hPG、HbA1c及血脂水平变化。结果观察组总有效率(86.54%)显著高于对照组(67.31%)(P<0.05);二组患者FPG、2hPG、HbA1c治疗前比较差异无统计学意义(P>0.05);二组患者FPG、2hPG、HbA1c治疗后均较治疗前明显降低(P<0.05);观察组患者FPG、2hPG、HbA1c治疗后均明显低于对照组(P<0.05);二组各血脂指标水平治疗前比较无差异统计学意义(P>0.05);二组患者TG、TC治疗后较治疗前明显减少(P<0.05),而HDL-C、LDL-C治疗后较治疗前无明显变化(P>0.05);观察组患者TG、TC治疗后显著低于对照组(P<0.05);治疗期间不良反应发生情况比较。结论中西医结合治疗2型糖尿病临床疗效显著,不良反应少,安全可靠,值得进一步推广应用。
Objective To explore the clinical efficacy and adverse reactions of traditional Chinese and western medicine in the treatment of type 2 diabetes mellitus. Methods 104 patients with type 2 diabetes were randomly divided into two groups, control group and observation group, with 52 cases in each group. The control group was treated with western medicine, and the observation group was treated with traditional Chinese medicine on the basis of the control group. The course of treatment was 12 weeks. The curative effect of the two groups were observed. The changes of FPG, 2hPG, HbA1c and blood lipid level before and after treatment were observed. Results The total effective rate (86.54%) in observation group was significantly higher than that in control group (67.31%) (P <0.05). There was no significant difference in FPG, 2hPG and HbA1c between the two groups before treatment (P> 0.05) FPG, 2hPG and HbA1c were significantly lower than those before treatment (P <0.05). FPG, 2hPG and HbA1c in the observation group were significantly lower than those in the control group after treatment (P <0.05) There was no significant difference between the two groups (P> 0.05). The TG and TC in the two groups were significantly lower than those before treatment (P <0.05), but no significant change after treatment with HDL-C and LDL-C ). The TG and TC levels in the observation group were significantly lower than those in the control group (P <0.05). The incidence of adverse reactions in the observation group was compared. Conclusion The treatment of type 2 diabetes mellitus with integrated traditional Chinese and western medicine has obvious curative effect, less adverse reactions, safe and reliable, which deserves further popularization and application.