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伤口愈合过程中复杂的生化及细胞活动在免疫系统的调节之下才能完成.免疫系统的巨噬细胞通过分泌单核细胞因子(monokine)影响上皮细胞和成纤维细胞的活动.T细胞分泌的淋巴因子对成纤维细胞的迁移、复制和胺元的合成起着正反的双重作用,T细胞缺乏也影响伤口愈合,表现为胶元缺如,张力减弱.T淋巴细胞在胸腺内成熟并获得功能.但胸腺在纤维组织形成中的作用尚不清楚.作者曾观察到切除成年动物胸腺后伤口容易化脓,由此推测胸腺对正常伤口愈合起抑制作用.为此作者进一步做了研究.
Complex biochemical and cellular activities during wound healing can be accomplished under the regulation of the immune system, which affects the activity of epithelial cells and fibroblasts through the secretion of monokines.Lymphs secreted by T cells Factor on fibroblast migration, replication and amine synthesis plays a dual role of positive and negative, T cell deficiency also affects wound healing, showed lack of collagen, tension weakened.T lymphocytes mature and gain function in the thymus However, the role of the thymus in the formation of fibrous tissue remains unclear, and the authors have observed that the wound is easy to purulent after removal of the thymus in adult animals, suggesting that the thymus has an inhibitory effect on the healing of normal wounds.