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屏气受多种因素影响,Schneider 观察到快速登高时,最大的屏气降低,而且在以后的几天内进一步降低.Godfrey 等提出,缺氧时PCO_2升高和缺乏正常的呼吸运动是影响屏气的两个动态因素.作者观察了快速登高时乙酰唑胺对屏气的影响,认为该药引起动脉血pH 降低的呼吸反应,在预防急性高山病中是一个重要因素。20例健康者11天步行登高到4846m,受试者随机分服安慰剂或乙酰唑胺500 mg/d.屏气从正常呼气终止时计时。结果两组的屏气时间随高度增加而减少.安慰剂组在登高的初期屏气时间迅速缩短,但以后
The breath-hold is affected by a number of factors, and Schneider observed that the maximum hold-off was reduced during rapid ascent and further decreased over the next few days. Godfrey et al. Suggested that elevated PCO2 and lack of normal breathing during hypoxia are two A Dynamic Factor The authors observed the effect of acetazolamide on breath holding ascent to rapid ascension and considered the drug’s respiratory response to decreased arterial pH and was an important factor in the prevention of acute mountain sickness. Twenty healthy subjects climbed to an altitude of 4846 m on an 11-day walk and were randomized to either placebo or acetazolamide 500 mg / d. The breath-hold timed from termination of normal expiration. Results The breath-hold time of both groups decreased with increasing height.The placebo group rapidly shortened the initial breath-hold time,