氟喹诺酮类抗菌药与其他药物的交互作用主要分为下列两类:1.影响氟喹诺酮类胃肠道的吸收Haffken 等首先报道环丙氟哌酸与含镁铝抗酸剂同时服,前者血清活性几乎全部消失。Schehtag 等的研究结果指出,镁铝抗酸剂在服用环丙氟哌酸前6小时或后2小时给予,对环丙氟哌酸的吸收无重大影响。临床上也有环丙氟哌酸治疗泌尿系感染时同服抗酸剂而治愈的例子。但是,多数人仍主张二者应尽量避免合用。最近试验指出,碳酸钙 Fluoroquinolone antibacterial drugs interact with other drugs can be divided into the following two categories: 1. Affect the absorption of fluoroquinolones gastrointestinal tract Haffken first reported that ciprofloxacin and magnesium aluminum anti-acid agent while serving the former serum Activity almost disappeared. The results of Schehtag et al. Show that magnesium-aluminum antacids given 6 hours or 2 hours after taking ciprofloxacin have no significant effect on the absorption of ciprofloxacin. Clinically, there is also ciprofloxacin treatment of urinary tract infection with the same antacid and cure cases. However, most people still maintain that both should be avoided as much as possible. Recent tests have pointed out that calcium carbonate