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目的综合评价子宫内膜癌发病的危险因素。方法收集国内有关子宫内膜癌危险因素的病例对照研究文献13篇,采用可信区间方差分析法计算各相关因素的ORc及95%CI。结果使用宫内节育器年数>1年、口服避孕药、有生育史、饮酒为子宫内膜癌的保护因素;糖尿病、高血压、肥胖、初潮年龄≤12岁、不孕等为子宫内膜癌的危险因素。结论子宫内膜癌的发病不仅与糖尿病、高血压等慢性病有关,还与月经、生育因素密切相关。应注意控制相关危险因素,加强妇女保健,做好高危人群的定期普查。
Objective To evaluate the risk factors of endometrial cancer. Methods Thirteen articles of case-control study on the risk factors of endometrial cancer in China were collected, and the ORC and 95% CI of each related factor were calculated by the method of confidence analysis of variance (ANOVA). Results The number of IUDs> 1 year, oral contraceptives, fertility history, alcohol consumption as a protective factor of endometrial cancer; diabetes, hypertension, obesity, menarche age ≤ 12 years, infertility and other endometrial cancer Risk factors. Conclusion The incidence of endometrial cancer is not only related to chronic diseases such as diabetes mellitus and hypertension, but also to menstruation and fertility factors. Care should be taken to control the relevant risk factors, strengthen women’s health, and do a regular census of high-risk groups.