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目的探讨重型颅脑损伤患者并发急性肾功能衰竭的危险因素。方法收集812例重型颅脑损伤患者相关临床资料,设立ARF(急性肾功能衰竭)组与非ARF组,采用X~2检验,进行统计学处理。结果 812例患者中有56例并发ARF,ARF组与非ARF组死亡率分别为33.93%、20.11%,两组间有非常显著性差异。统计结果显示,年龄、伤情、低血容量、高血浆渗透压、多脏器功能损害与ARF的发生显著相关。结论 ARF进一步增加了重型颅脑损伤患者的死亡率,高龄、低GCS评分、低血容量、高血浆渗透压、上消化道出血并肺部感染是ARF发生的危险因素。
Objective To investigate the risk factors of acute renal failure in patients with severe traumatic brain injury. Methods The clinical data of 812 patients with severe craniocerebral injury were collected. Acute renal failure (ARF) group and non-ARF group were established. X ~ 2 test was used for statistical analysis. Results 56 cases of 812 patients complicated with ARF, ARF and non-ARF mortality were 33.93%, 20.11%, there was a significant difference between the two groups. Statistics show that age, injury, hypovolemia, high plasma osmotic pressure, multiple organ dysfunction and ARF were significantly correlated. Conclusions ARF further increases the mortality rate, elderly, low GCS score, hypovolemia, high plasma osmotic pressure, upper gastrointestinal bleeding and pulmonary infection in ARF patients.