一、背景在化学药物对辐射反应的修饰作用的研究中,着重点总是主要针对但不是唯一针对着放射增敏药物或放射防护药物在放疗中的利用问题。在放射增敏剂领域中,有关放射增敏机制所作的大量工作总是会导致一大群化合物的发现,而这些化合物对处于低氧条件下的细胞明显表示出各种不同的增敏效应,但对处于富氧条件下的细胞却没有作用。对氧效应的普遍性的放射生物学研究以及许多种具有“放射抗性”肿瘤的 I. Background In the study of the role of chemical drugs in the modification of radiation response, the focus has always been on but not exclusively on the use of radiation-sensitizing drugs or radioprotective drugs in radiotherapy. In the field of radiosensitizers, a large amount of work on radiosensitization mechanisms will always lead to the discovery of a large group of compounds, and these compounds clearly show various sensitization effects on cells under hypoxic conditions. There is no effect on cells under oxygen-rich conditions. Universal radiobiological studies of the effects of oxygen and many types of tumors that are “radioresistant”