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目的:观察三阴交穴位注射缩宫素对防治产妇产后出血的影响。方法:将400例产妇随机均分为A、B、C、D组。胎儿娩出后、胎盘娩出前,A组产妇于三阴交穴位处注射缩宫素10 U;B组产妇不使用任何药物,单针刺于三阴交穴位;C组产妇于小腿内侧,当足内踝尖上3寸,非穴位处注射缩宫素10 U;D组产妇于臀部肌肉注射缩宫素10 U。观察4组产妇产后2 h内、24 h内出血例数及平均出血量,并记录不良反应发生情况。结果:A组产妇产后2 h内出血量在<100 ml、100~200 ml范围内的例数显著高于B、C、D组,产后出血量>200 ml例数显著低于B、C、D组,差异有统计学意义(P<0.05)。A组产妇产后24 h内出血量<200 ml的例数显著高于B、C、D组,产后出血量在200~500 ml、>500 ml的例数均显著低于B、C、D组,差异有统计学意义(P<0.05)。A组产妇产后2 h内、24 h内平均出血量显著低于B、C、D组,差异有统计学意义(P<0.05),而B、C、D组间比较,差异无统计学意义(P>0.05)。4组产妇治疗期间均未见明显不良反应发生。结论:三阴交穴位注射缩宫素能有效地减少产妇产后的出血量,安全性亦较好。
Objective: To observe the effect of injection of oxytocin at Sanyinjiao on prevention and treatment of postpartum hemorrhage. Methods: 400 mothers were randomly divided into A, B, C and D groups. A group of mothers in the Sanyinjiao point injection of oxytocin 10 U; B group of mothers do not use any drugs, single acupuncture points in the Sanyinjiao; C group maternal in the medial calf, when the tip of the medial malleolus 3 Inch, non-acupoint injection of oxytocin 10 U; D group of mothers in the buttocks muscle injection of oxytocin 10 U. Observe the 4 groups of maternal 2 h postpartum within 24 h, the number of cases of bleeding and the average amount of bleeding, and record the incidence of adverse reactions. Results: In group A, the amount of bleeding in <100 ml and 100-200 ml was significantly higher in group B than in group B, C and D, and the number of postpartum hemorrhage> 200 ml was significantly lower than that in group B, C and D Group, the difference was statistically significant (P <0.05). In group A, the number of cases with bleeding less than 200 ml within 24 h postpartum was significantly higher than that in groups B, C and D. The number of cases with postpartum hemorrhage ranging from 200 to 500 ml and> 500 ml were significantly lower than those in groups B, C and D, The difference was statistically significant (P <0.05). The average amount of bleeding within 24 hours after birth in group A was significantly lower than that in groups B, C and D (P <0.05), but there was no significant difference between groups B, C and D (P> 0.05). No significant adverse reactions occurred during the 4 groups of maternal treatment. Conclusion: Injection of oxytocin at Sanyinjiao point can effectively reduce the amount of postpartum hemorrhage and has good safety.