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目的探讨轮状病毒感染患儿并发心肌炎的临床治疗方法及效果,为该病治疗提供参考依据。方法采取回顾性方法对2013年9月-2015年9月50例轮状病毒感染并发心肌炎住院患儿的临床资料进行分析;密切监测其心电图变化;所有患儿均于治疗前后静脉采血2ml,检测乳酸脱氢酶(LDH)、肌钙蛋白-T(cTnT)和血清肌酸激酶(CK)以及肌酸激酶同工酶(CK-MB)的变化;同时观察其心肌酶恢复正常和住院时间,及治疗过程中的不良反应。结果 50例患儿出院时心肌酶均恢复正常,恢复正常时间为(17.92±4.51)d,住院时间为(21.54±3.26)d;治疗过程中无严重并发症发生;50例患儿LDH、cTnT、CK和CK-MB含量治疗后均较治疗前明显的降低,差异有统计学意义(P<0.05)。结论临床中对于轮状病毒感染患儿并发心肌炎,应尽早的给予对症支持治疗,从而改善其临床症状与体征;同时,综合性治疗可以改善患儿心肌功能,并提高临床整体疗效。
Objective To investigate the clinical treatment of myocarditis in children with rotavirus infection and its clinical effects, and to provide a reference for the treatment of the disease. Methods The clinical data of 50 hospitalized children with rotavirus infection complicated with myocarditis from September 2013 to September 2015 were retrospectively analyzed. The electrocardiographic changes were monitored closely. All children received 2ml venous blood before and after treatment, Lactate dehydrogenase (LDH), troponin-T (cTnT) and serum creatine kinase (CK) as well as creatine kinase isoenzyme (CK-MB) And adverse reactions in the course of treatment. Results All of the 50 patients returned to normal after discharge, the time to return to normal was (17.92 ± 4.51) days and the hospitalization time was (21.54 ± 3.26) days. No serious complications occurred during the course of treatment. The LDH, cTnT , CK and CK-MB content after treatment were significantly lower than before treatment, the difference was statistically significant (P <0.05). Conclusions In clinic, children with rotavirus infection complicated with myocarditis should be given symptomatic supportive treatment as early as possible so as to improve their clinical symptoms and signs. At the same time, comprehensive treatment can improve myocardial function and improve overall clinical efficacy.