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降纤酶是由多组分的蝮蛇抗栓酶经提取、纯化得到的单一组分的蛇毒酶,相对分子最小,从而避免了多组分蝮蛇抗栓酶可能有的神经毒性和出血的副作用为观察降纤酶治疗短暂性脑缺血发作(TIA)的疗效和安全性,我们自1997年10月至1999年2月以降纤酶治疗TIA 30例,25例做对照,现报告如下。 1 资料和方法 1.1 病例选择 入选者55例,所有患者做头部CT排除脑出血和脑梗塞,经详细询问病史,均符合1995年全国第四届脑血管疾病学术会议诊断标准,并除外有以下情况者:①有出血倾向者;②有严重肝、肾功能障碍者;③3天内使用抗凝或溶栓药物者
Defibrase is a single component of the snake venom enzyme extracted and purified from the multi-component viper antithrombin, with the smallest relative molecular weight, thus avoiding the possible neurotoxicity and bleeding of the multi-component viper antithrombin Side effects To observe the efficacy and safety of defibrase in the treatment of transient ischemic attacks (TIA), we from October 1997 to February 1999 defibrase treatment of TIA in 30 cases, 25 cases of control, are as follows. 1 Materials and Methods 1.1 Case Selection 55 cases, all patients with head CT to rule out cerebral hemorrhage and cerebral infarction, after a detailed history, are in line with the Fourth National Conference on Cerebrovascular Disease in 1995 diagnostic criteria, with the exception of the following Situation: ① bleeding tendency; ② severe liver and kidney dysfunction; ③ 3 days use of anticoagulant or thrombolytic drugs