胸腺是T细胞分化和成熟的主要器官,但有关T细胞在胸腺内分化发育的过程及机制尚未完全明了.虽然已有充分资料证实Goldstein和Bach等发现的胸腺素和血清胸腺因子等胸腺激素能诱导T细胞的分化和成熟,但最近Andrews等用有限稀释法的实验表明目前各种胸腺激素制剂并不能诱导不成熟胸腺皮质细胞的功能发育.早年曾观察到新生期去胸腺小鼠腹腔埋植含胸腺的微孔扩散盒后,免疫功能 Thymus is the main organ of T cell differentiation and maturation, but the process and mechanism of differentiation and development of T cells in thymus have not been fully understood.Although there is sufficient data to confirm that the thymosin and thymus factors such as thymosin and serum thymus found by Goldstein and Bach et al Induced differentiation and maturation of T cells, but recent experiments by limited dilution methods by Andrews et al show that various thymic hormone preparations can not induce the functional development of immature thymic cortical cells. In early years, it has been observed that neonatal thymus mice are implanted in the abdominal cavity Thymus-containing microporous diffusion box, immune function