本文采用液相微萃取/后萃取(LPME/BE)与高效液相色谱联用法萃取并测定了中药厚朴及其制剂—藿香正气口服液和香砂养胃丸中厚朴酚与和厚朴酚的含量。优化了萃取效率影响因素,萃取溶剂、供相与接受相、转速及萃取时间。厚朴酚与和厚朴酚的线性范围分别为1.56-156μg/mL和1.10-110μg/mL;检测限(S/N=3)分别为0.10μg/mL和0.07μg/mL,回收率范围为98.3%-105.1%,RSD<2.5%。 In this paper, liquid phase micro extraction/post-extraction (LPME/BE) and high performance liquid chromatography were used to extract and determine the traditional Chinese medicine Houpu and its preparations - Huxiangzhengqi Oral Liquid and Xiangsha Yangwei Pills, magnolol and honokiol Phenol content. The factors affecting extraction efficiency, extraction solvent, donor phase and acceptor phase, rotation speed and extraction time were optimized. The linear ranges of honokiol and honokiol were 1.56-156 μg/mL and 1.10-110 μg/mL, respectively; the detection limits (S/N=3) were 0.10 μg/mL and 0.07 μg/mL, respectively, and the recoveries were in the range of 98.3%-105.1%, RSD <2.5%.