肝功能衰竭者昏迷的发病机制,可由各种不同原因所引起,而血氨浓度升高却是重要原因之一。及二氏早在1893年将肉类喂饲有氏瘻管的狗,因其肠内氨代谢产物未经肝脏解毒,引起中毒死亡。Burchi氏(1927)首先发现肝硬 The pathogenesis of coma in patients with liver failure can be caused by a variety of causes, and elevated blood ammonia concentration is one of the important reasons. As early as 1893, the two dogs fed fistula meat to the meat, causing poisoning and death due to the detoxification of ammonia metabolites in the intestine without liver. Burchi’s (1927) first found liver cirrhosis