James Lind的著名试验——柑桔类水果可以治疗坏血病的其中一个惊人之处是,他不仅忽略了自己的试验证据,而且在临床实践中继续倡导那些他已经发现无效的治疗,包括应用含硫酸的物质。医学史上充满了曾经是临床通用但现在被证明是无效甚至是对患者有害的治疗先例:由于法国的外科医生Pare恰好 One of the striking aspects of James Lind’s famous trial of citrus fruits for the treatment of scurvy is that he not only ignored his own experimental evidence but also continued to advocate in clinical practice for those he has found to be ineffective, including the use of Sulfuric acid containing substances. History of medicine is full of precedent for treatment that used to be clinically common but now proved to be ineffective or even harmful to the patient: as French surgeon Pare happens to be fine