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为探讨比格犬和C3H小鼠对犬埃立克体的敏感性 ,建立犬埃立克体病实验模型 ,用我国埃立克体病病犬血白细胞分别接种比格犬和C3H小鼠。接毒后比格犬和C3H小鼠均为PCR阳性 ,比格犬与最易感的德国牧羊犬自然感染埃立克体病的临床表现和病理学变化基本一致。结果表明比格犬和C3H小鼠对犬埃立克体均有较高敏感性
In order to investigate the sensitivity of Beagle dogs and C3H mice to Ehrlichia canines, an experimental model of Ehrlichiosis canine was established. Beagle dogs and C3H mice were inoculated with Ehrlichia canine leukocytes. Beagle dogs and C3H mice were all PCR-positive after receiving the virus. The clinical manifestations and pathological changes of ehrlichiosis naturally infected by beagle dogs and the most susceptible German Shepherd dogs were basically the same. The results show that beagle dogs and C3H mice have high sensitivity to ehrlichia