自发性卵巢早衰(POF)指40岁前出现的非化疗、射线或手术所致的闭经伴高促性腺激素低雌激素综合征。表现在卵巢内分泌功能的丧失以及不育并造成深层次的心理影响。学者认为卵泡刺激素(FSH)达绝经水平就是“卵巢功能不可逆停止”的标志,但并非如此,约50%的“早衰”者在之后的多年 Spontaneous Premature Ovarian Failure (POF) refers to non-chemotherapy, radiological or surgical amenorrhea accompanied by hypo-gonadotropin-low estrogen syndrome before age 40 years. Performance in the ovarian endocrine function loss and infertility and cause deep psychological effects. Scholars believe that follicle stimulating hormone (FSH) up to menopause level is “a sign of irreversible ovarian function stop,” but not so, about 50% of “premature aging” in the years after