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目的 :观察尼莫地平治疗急性脑出血的临床疗效。方法 :应用前瞻性随机单盲方法 ,对 96例经CT证实为急性脑出血病人 ,在起病 4 8h内随机分为治疗组和对照组 ,治疗前后比较两组病人神经功能缺损程度积分差及颅内血肿体积 ,血肿周围水肿带面积的改变。结果 :尼莫地平治疗组较对照组血肿周围水肿带面积明显缩小 (P <0 0 5 ) ,神经功能缺损评分明显改善 (P <0 0 1) ,血肿体积则改变不明显。结论 :在脑出血急性期应用尼莫地平治疗 ,可明显改善其病情
Objective: To observe the clinical efficacy of nimodipine in the treatment of acute cerebral hemorrhage. Methods: One hundred and sixty-six patients with acute cerebral hemorrhage confirmed by CT were randomly divided into treatment group and control group within 48 hours after onset. The difference of neurological deficit scores before and after treatment was compared between two groups Intracranial hematoma volume, hematoma area around the edema change. Results: Compared with the control group, the area of edema around the nimodipine treatment group was significantly reduced (P <0 05), the neurological deficit score was significantly improved (P 0 01), and the volume of hematoma was not changed significantly. Conclusion: The application of nimodipine in the acute stage of cerebral hemorrhage can obviously improve its condition