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目的通过回顾性分析中山市围产儿出生缺陷水平变化情况,探讨其影响因素,为卫生行政部门制订决策提供依据。方法对2000年至2008年中山市围产儿出生缺陷资料进行分析。结果 2000年至2008年围产儿平均出生缺陷发生率为102/万,呈上升趋势。出生缺陷发生前5位的是:先天性心脏病、唇腭裂、神经管畸形、并多指(趾)、α-地中海贫血。结论应进一步加强宣教、加强提高产前筛查水平及产前诊断,降低围产儿出生缺陷发生率。
Objective To retrospectively analyze the changes of birth defects in perinatal infants in Zhongshan City and explore the influencing factors so as to provide basis for the health administrative departments to make decisions. Methods The data of birth defects in perinatal infants from 2000 to 2008 in Zhongshan were analyzed. Results Between 2000 and 2008, the average incidence of perinatal birth defects was 1.02 million, showing an upward trend. The first five birth defects are: congenital heart disease, cleft lip and palate, neural tube defects, and multi-fingered (toe), alpha-thalassemia. Conclusion The missionary education should be further strengthened to increase the level of prenatal screening and prenatal diagnosis and reduce the incidence of perinatal birth defects.