目的评价经直肠超声引导下前列腺穿刺活检的临床价值。方法对临床高度怀疑前列腺癌86例患者进行经直肠超声引导下前列腺穿刺活检。结果经病理证实前列腺癌34例,前列腺增生41例,不典型增生2例,前列腺内皮瘤3例,前列腺慢性炎症4例,鳞状上皮化生1例,结核1例。3例患者声像图未显示前列腺占位病变但穿刺活检为前列腺癌,而2例前列腺特异性抗原异常增高的患者穿刺活检为前列腺增生。结论经直肠超声引导下前列腺穿刺活检术操作简单、准确性高、安全、并发症极少,在临床早期诊断前列腺癌很有价值,为选择治疗方案提供指导。 Objective To evaluate the clinical value of transrectal ultrasound guided prostate biopsy. Methods Eighty-six patients with clinically suspected prostate cancer underwent transrectal ultrasound guided prostate biopsy. Results There were 34 cases of prostate cancer, 41 cases of benign prostatic hyperplasia, 2 cases of atypical hyperplasia, 3 cases of prostatic intraepithelial neoplasia, 4 cases of chronic inflammation of the prostate, 1 case of squamous metaplasia and 1 case of tuberculosis. The sonography of the 3 patients did not show the lesions of the prostate but the biopsy of the prostate showed prostate cancer, whereas the biopsy of 2 patients with abnormally elevated prostate-specific antigen was prostatic hyperplasia. Conclusions Transrectal ultrasound-guided prostate biopsy is simple, accurate, safe and has few complications. It is valuable in the early diagnosis of prostate cancer and provides guidance for the selection of treatment options.