正常妊娠时,母体处于生理性高雌激素状态,但除此之外,随着环境污染的加重,环境中存在大量雌激素活性物质,有一定的内分泌干扰效应;辅助生殖治疗中,早孕期的母体也处于高雌激素状态,而胚胎在发育时期对外界影响十分敏感,各种因素可导致胚胎发育异常,从而导致早期胚胎死亡或者胎? Normal pregnancy, the mother in a state of physiological high estrogen, but in addition, with the increase of environmental pollution, the environment there is a large number of estrogen active substances, have some endocrine disrupting effect; assisted reproductive therapy, early pregnancy The mother is also in a state of high estrogen, and embryos are very sensitive to the outside world during development. Various factors can lead to abnormal embryogenesis, leading to early embryonic death or fetal death.