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为了降低儿童糖尿病酮症酸中毒(DKA)的发病率,提高儿科治疗DKA的成功率。回顾分析了25年胰岛素依赖型糖尿病住院儿童114例(其中DKA 53例)的资料。1990年～1998年和1974年～1979年或1980年～1989年比较,DKA发病率明显下降(P<0.05)。年龄越小,DKA发病率越高,父母文化程度低的农村儿童发病率明显高于城镇儿童。DKA的诱因中,感染列首位(49.1％),停用胰岛素其次(20.8％)。减少使用碳酸氢盐量的一组,其代谢恢复及住院时间均较剂量较大的两组明显缩短(P<0.05)。提示:加强小儿糖尿病管理力度非常重要。较大剂量碳酸氢盐对治疗DKA有潜在的不利因素。
In order to reduce the incidence of diabetic ketoacidosis (DKA) and improve the success rate of pediatric treatment of DKA. Retrospective analysis of 25 years of insulin-dependent diabetes in 114 children (including 53 cases of DKA) data. The incidence of DKA decreased significantly from 1990 to 1998 and from 1974 to 1979 or from 1980 to 1989 (P <0.05). The younger the higher the incidence of DKA, the incidence of rural children with a low educational level of parents is significantly higher than that of urban children. Among the causes of DKA, infection was the top (49.1%), followed by insulin (20.8%). A reduction in the use of bicarbonate dose group, the metabolic recovery and hospitalization were significantly shorter than the two groups were significantly reduced dose (P <0.05). Tip: Strengthening pediatric diabetes management is very important. Higher doses of bicarbonate have potential disadvantages for treating DKA.