目的:探讨在肝癌治疗中分别应用腹腔镜切除术与经皮穿刺微波消融术对患者预后影响。方法:从我院2010年3月至2012年3月收治的肝癌患者中选取90例为研究对象,经随机数字表法分为A组45例,B组45例,A组行经皮穿刺微波消融术治疗,B组行腹腔镜切除术治疗,观察两组患者手术时间、术中出血量及预后效果。结果:A组患者手术时间及术中出血量情况明显优于B组(P<0.05);A组并发症发生为6.67%,同B组比较,明显较低(P<0.05);A组局部复发率为20.00%,同B组8.89%比较,明显较高(P<0.05),总复发率无明显差异(P>0.05);两组患者术后1、2、3年存活率均无明显差异(P>0.05)。结论:在肝癌治疗中,经皮穿刺微波消融术与腹腔镜切除远期疗效均较好,经皮穿刺微波消融术创伤小,并发症发生率低,对预后改善具有重要作用。 Objective: To investigate the effects of laparoscopic and percutaneous microwave ablation on the prognosis of patients with liver cancer. Methods: Totally 90 cases of HCC from March 2010 to March 2012 in our hospital were selected and divided into 45 cases in group A, 45 cases in group B, and group A were treated by microwave ablation The patients in Group B underwent laparoscopic resection. The operation time, intraoperative blood loss and prognosis were observed. Results: The operation time and intraoperative blood loss in group A were significantly better than those in group B (P <0.05). The incidence of complications in group A was 6.67%, which was significantly lower than that in group B (P <0.05) The recurrence rate was 20.00%, which was significantly higher than that of 8.89% in group B (P <0.05). There was no significant difference in the total recurrence rate between the two groups (P> 0.05). There was no significant difference between the two groups Difference (P> 0.05). Conclusion: The long-term curative effect of percutaneous microwave ablation and laparoscopic resection is good in the treatment of liver cancer. Percutaneous microwave ablation is less traumatic and the incidence of complications is low, which plays an important role in the prognosis improvement.