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与感染相关的婴儿肝炎综合征可由多种病原引起,包括嗜肝病毒及非嗜肝病毒、细菌、弓形体、梅毒螺旋体等。主要临床表现为婴儿期(包括新生儿期)发病,肝功能异常,肝大、质地改变,伴有肝细胞性黄疸(血结合胆红素和未结合胆红素均增高)。需要与遗传代谢病、药物引起的肝损伤或肝胆系统先天畸形鉴别。治疗原则为保肝、利胆、营养和病因治疗。预后因病原而异。
Infant hepatitis syndrome associated with infection can be caused by a variety of pathogens, including hepadnavirus and non-hepadnavirus, bacteria, toxoplasmosis, treponema pallidum and the like. The main clinical manifestations of infancy (including neonatal) disease, abnormal liver function, liver, texture changes, accompanied by hepatocellular jaundice (blood conjugated bilirubin and unconjugated bilirubin were increased). Need and genetic metabolic diseases, drug-induced liver injury or liver and gallbladder system congenital malformations identification. The principle of treatment for the liver, gallbladder, nutrition and cause of treatment. Prognosis varies by pathogen.