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近年来,我院应用维生素K_1治疗婴幼儿顽固性细菌性痢疾(菌痢)40例,疗效较好,现报告如下。 临床资料:将80例菌痢患儿(男44例,女36例;新生儿30例,～2岁50例)随机分为治疗组40例,对照组40例。患者均曾在外院治疗7～10天,病情无好转,经大便培养确诊。主要表现为发热、腹痛、腹泻,脓血粘液便伴里急后重,个别合并有肺炎、硬肿症、颅内出血等,大便常规镜检均有红细胞、脓细胞,个别有巨噬细胞。 治疗方法:根据药敏应用抗生素并常规补液,给予支持疗法、对症处理、治疗合并症等。治疗组在以上治疗基础上,加用维生素K_11～2mg/(kg·次)。
In recent years, our hospital application of vitamin K_1 treatment of infantile refractory bacillary dysentery (bacillary dysentery) 40 cases, the effect is better, are as follows. Clinical data: 80 cases of dysentery in children (44 males and 36 females; 30 newborns, 50 cases of ~ 2 years old) were randomly divided into treatment group 40 cases and control group 40 cases. Patients were treated in the hospital for 7 to 10 days, the condition did not improve, confirmed by stool culture. The main manifestations of fever, abdominal pain, diarrhea, pus and mucus with tenesmus, individual merger with pneumonia, scleredema, intracranial hemorrhage, stool routine examination of red blood cells, pus, some have macrophages. Treatment: According to the application of antibiotics antibiotics and routine rehydration, given supportive therapy, symptomatic treatment, treatment of complications. Treatment group in the above treatment based on the addition of vitamin K_11 ~ 2mg / (kg · times).