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报告1例威尔尼克外瓶霉致掌黑癣。患者女,24岁。右手大鱼际淡褐色椭圆形斑块4年余,无不适。皮损鳞屑真菌镜检:10%KOH涂片可见浅棕色短菌丝及出芽孢子,美蓝涂片染色可见短菌丝及孢子。皮屑培养生长缓慢,初期为灰白色至橄榄色酵母样菌落,很快变为墨绿色至黑色菌落。菌落表面可见絮状、暗灰色至绿灰色气生菌丝。对培养菌株行土豆培养基小培养观察形态学符合威尔尼克外瓶霉,用扫描电镜观察其产孢方式为环痕产孢、合轴式排列方式,菌丝两侧及顶端有环痕梗,环孢子聚集在环痕梗周围。基因测序与标准菌株GQ334387.1(GI:254802560)威尔尼克外瓶霉具有100%同源性。诊断为掌黑癣。给予5%硝酸舍他康唑乳膏每日2次外用,连用2周后皮损完全消退。随访3个月未见复发。
One case of Wilcoxomycosis was reported. Female patient, 24 years old. Right-handed large occasion light brown oval plaques more than 4 years, no discomfort. Lesions scaly fungus microscopic examination: 10% KOH smear visible light brown short mycelium and spores, the United States blue smear stained mycelium and spores. Dandruff growth slow, the initial gray to olive yeast-like colonies, quickly turned dark green to black colonies. Colony visible floc on the surface, dark gray to green gray aerial mycelium. The cultivation of strains of potato culture medium was observed in line with small morphological culture of Vernier vial, with a scanning electron microscopy of sporozoite ring sporozoites, coaxial arrangement, both sides of mycelium and the top ring ring stems Circumspores accumulate around the ring marks. Gene sequencing was 100% homologous to the standard strain GQ334387.1 (GI: 254802560) Vernonia villosana. Diagnosis of palm black ringworm. Give 5% sertaconazole nitrate cream 2 times a day topical, once every 2 weeks after the skin lesions completely subsided. Follow-up 3 months no recurrence.