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目的探讨输卵管妊娠患者生殖道支原体和衣原体的感染情况,为临床输卵管妊娠的诊治提供依据。方法选择2011年3月-2015年3月诸暨市妇幼保健院妇科住院手术治疗的输卵管妊娠患者128例作为研究组,同时选择同期住院手术治疗的附件良性囊肿患者128例作为对照组。观察输卵管妊娠组和对照组的临床资料、下生殖道支原体和衣原体检测结果,输卵管妊娠次数和下生殖道支原体和衣原体感染的关系,输卵管妊娠患者术后输卵管造影情况。结果研究组的年龄和对照组相比,差异无统计学意义(P>0.05),研究组的不孕史、宫颈炎史、盆腔炎史以及术中粘连的比例均明显高于对照组(P<0.05)。研究组的支原体阳性率、衣原体阳性率以及支原体+衣原体阳性率均明显高于对照组(P<0.05)。输卵管妊娠≥2次组的衣原体阳性率以及支原体+衣原体阳性率均明显高于输卵管妊娠1次组(P<0.05),输卵管妊娠≥2次组的支原体阳性率稍高于输卵管妊娠1次组,但差异无统计学意义(P>0.05)。对于输卵管妊娠术后有生育要求的患者进行输卵管造影,输卵管妊娠支原体阳性19例,输卵管造影通畅15例;输卵管妊娠衣原体阳性8例,输卵管造影通畅5例。两组输卵管通畅率之间比较,差异无统计学意义(P>0.05)。结论输卵管妊娠和下生殖道感染密切相关,下生殖道支原体和衣原体感染是输卵管妊娠的常见病原菌,对输卵管妊娠患者进行生殖道支原体和衣原体筛查具有重要意义。
Objective To investigate the infection of Mycoplasma genitalium and Chlamydia in patients with tubal pregnancy and provide evidence for the clinical diagnosis and treatment of tubal pregnancy. Methods 128 cases of tubal pregnancy treated by gynecology in Zhuji Maternal and Child Health Hospital from March 2011 to March 2015 were selected as the research group and 128 cases of benign cyst attached cysts were selected as the control group during the same period of hospitalization. Observe the clinical data of tubal pregnancy group and control group, the detection results of lower mycoplasma and chlamydia, the number of tubal pregnancy and the relationship between lower genital mycoplasma and chlamydia infection, and tubal pregnancy after tubal pregnancy. Results The age of the study group was not significantly different from the control group (P> 0.05). The infertility history, history of cervicitis, history of pelvic inflammatory disease and intraoperative adhesions in the study group were significantly higher than those in the control group (P <0.05). The study group’s mycoplasma positive rate, the positive rate of chlamydia and the positive rate of mycoplasma + chlamydia were significantly higher than the control group (P <0.05). The positive rates of chlamydia and mycoplasma + chlamydia were significantly higher than those of tubal pregnancy (P <0.05). The positive rate of mycoplasma in tubal pregnancy≥2 was slightly higher than that of tubal pregnancy, But the difference was not statistically significant (P> 0.05). For tubal pregnancy postoperative reproductive requirements of patients with tubal angiography, tubal pregnancy mycoplasma positive in 19 cases, tubal smooth patency in 15 cases; tubal pregnancy, chlamydia positive in 8 cases, tubal patency in 5 cases. The tubal patency rate between the two groups, the difference was not statistically significant (P> 0.05). Conclusions Tubal pregnancy and lower genital tract infection are closely related. Mycoplasma genitalis and chlamydial infection are common pathogens of tubal pregnancy, which is of great significance for the screening of Mycoplasma genitalium and Chlamydia in tubal pregnancy patients.