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目的:提高对原发性附睾腺癌的认识。方法:回顾性分析2例原发性附睾腺癌患者的临床资料:2例肿瘤均位于右侧,累及附睾体部、尾部及精索,其中1例发现有远处转移。1例行右侧精索、附睾、睾丸高位切除术,另1例行右睾丸、附睾、精索根治性切除术并腹膜后淋巴结清扫术。结果:1例病理检查报告为右侧附睾乳头状腺癌伴慢性炎症,随访至今未见转移及其他异常;另1例报告为右附睾腺癌,部分累及睾丸,术后5个月死于多器官功能衰竭。结论:原发性附睾腺癌早期确诊困难,病程进展快,预后差。手术是首选治疗手段,放疗和化疗尚缺乏临床经验。
Objective: To improve the understanding of primary epididymal adenocarcinoma. Methods: The clinical data of 2 patients with primary epididymal adenocarcinoma were retrospectively analyzed. Tumors in two cases were located on the right side, involving the body, tail and spermatic cord of the epididymis. One of them had distant metastasis. 1 case of right spermatic cord, epididymis, testicular high resection, and the other 1 case of right testes, epididymis, sphincter resection and retroperitoneal lymph node dissection. Results: One case of pathological examination reported papillary adenocarcinoma of the right epididymis with chronic inflammation and no metastasis and other abnormalities were observed up to now. Another case was reported as right epididymal adenocarcinoma with partial involvement of the testis and 5 months after operation Organ failure. Conclusion: Primary epididymal adenocarcinoma is difficult to diagnose in the early stage, the course of disease progresses rapidly and the prognosis is poor. Surgery is the preferred treatment, radiotherapy and chemotherapy is still lack of clinical experience.