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目的:探讨局部切除术在Vater壶腹癌治疗中的价值。方法:回顾性分析1997—2005年间收治的63例T1、T2期Vater壶腹癌患者临床资料,其中21例行局部切除(观察组),42例行胰十二指肠切除(对照组)。比较两组手术时间、术中出血量、术中输血量、术后并发症、术后住院时间及术后生存情况。结果:两组患者临床病理资料具有可比性(均P>0.05);与对照组比较,观察组平均手术时间、术中出血量、术中输血量、术后并发症发生率均明显降低(均P<0.05),但平均住院时间差异无统计学意义(P>0.05);两组术后生存率差异无统计学意义(P=0.131)。结论:局部切除术治疗T1、T2期Vater壶腹癌创伤小、并发症发生率低、术后生存率满意。
Objective: To investigate the value of partial resection in the treatment of Vater ampulla. Methods: The clinical data of 63 patients with Vater ampulla of T1 and T2 were retrospectively analyzed. Among them, 21 patients underwent partial resection (observation group) and 42 patients underwent pancreatoduodenectomy (control group). The operation time, intraoperative blood loss, intraoperative blood transfusion, postoperative complications, postoperative hospital stay and postoperative survival were compared between the two groups. Results: The clinicopathological data of the two groups were comparable (all P> 0.05). Compared with the control group, the average operation time, intraoperative blood loss, intraoperative blood transfusion and postoperative complications were significantly decreased P <0.05), but the average length of hospital stay was not significantly different (P> 0.05). There was no significant difference in postoperative survival between the two groups (P = 0.131). Conclusion: Local resection of Vater ampullary carcinoma of stage T1 and T2 has less trauma, less complication and satisfactory postoperative survival.