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目的:就不同药物治疗慢性心力衰竭的疗效进行对比研究。方法:选取2008年1月-2010年1月在我院就诊的66例慢性心力衰竭患者,他们的年龄为20～75岁,将他们随机分为2组,每组33例。两组患者均给予非洋地黄类正性肌力药物、洋地黄类强心药物、利尿剂、ACEI等常规抗心力衰竭治疗。同时,治疗组加用卡维地洛,对照组加用卡托普利。结果:治疗组33例患者中,显效(症状较治疗前明显减轻)25例(75.76%),有效(症状有所减轻)6例(18.18%),无效(治疗前后临床症状无改善)2例(6.06%),总有效率为31例(93.94%)。而对照组33例患者,显效(症状较治疗前明显减轻)20例(60.61%),有效(症状有所减轻)7例(21.21%),无效(治疗前后临床症状无改善)6例(18.18%),总有效率27例(81.82%)。结论:卡维地洛和卡托普利都能够有效改善慢性充血性心力衰竭患者的心功能,但卡维地洛的疗效要优于卡托普利。
Objective: To compare the efficacy of different drugs in the treatment of chronic heart failure. Methods: Sixty-six chronic heart failure patients from January 2008 to January 2010 in our hospital were selected. Their ages ranged from 20 to 75 years. They were randomly divided into two groups of 33 patients. Two groups of patients were given non-digitalis inotropic drugs, digitalis cardiac drugs, diuretics, ACEI and other conventional anti-heart failure treatment. At the same time, the treatment group plus carvedilol, control group plus captopril. Results: Among the 33 patients in the treatment group, there were 25 patients (75.76%) with effective (symptom relieved), 6 (18.18%) effective and (2 patients with no clinical symptom improvement) after treatment (6.06%), the total effective rate was 31 cases (93.94%). In the control group, 20 patients (60.61%) showed effective (symptom relieved significantly before treatment), 7 (21.21%) effective (alleviated symptoms), 6 patients (18.18 %), The total effective rate was 27 cases (81.82%). CONCLUSION: Both carvedilol and captopril can effectively improve cardiac function in patients with chronic congestive heart failure, but the efficacy of carvedilol is superior to that of captopril.