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目的:观察中西医结合的方法治疗排卵功能障碍性不孕症的临床疗效。方法:选择90例无排卵性不孕症患者,随机分为3组,每组30名。中药组(第1组)单纯采用促卵助孕汤治疗;西药组(第2组)采用克罗米芬(CC)+尿促性素(HMG)+绒毛膜促性腺激素(HCG)治疗;中西医结合组(第3组)采用促卵助孕汤配合西药治疗。比较各组治疗后2月内排卵率、周期排卵率、卵泡未破裂黄素化综合征发生率、周期卵泡未破裂黄素化综合征(LUFS)发生率和6月内妊娠率。结果:排卵率各组分别为46.67%,60.00%,86.67%,第3组显著高于第1、2组(P<0.01);周期排卵率各组分别为43.10%、57.89%、83.33%、第3组显著高于第1、2组(P<0.01);卵泡未破裂黄素化综合征发生率各组分别为13.33%、26.67%、3.33%,第3组低于第1、2组(P<0.05);周期卵泡未破裂黄素化综合征各组分别为13.79%,28.07%,3.70%,第3组显著低于第1、2组(P<0.01);6月内妊娠率各组分别为20.00%、40.00%、63.33%,第3组显著高于第1、2组(P<0.01)。结论:中西医结合治疗无排卵性不孕症,在增加排卵率及周期排卵率、减少卵泡未破裂黄素化综合征发生率及周期卵泡未破裂黄素化综合征发生率和升高6月内妊娠率方面,有着独特的疗效。而单纯中药治疗促排卵效果缓慢,单纯西药治疗易发生卵泡未破裂黄素化综合征及周期卵泡未破裂黄素化综合征。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of ovulatory dysfunction infertility. Methods: Ninety cases of anovulatory infertility were selected and randomly divided into three groups of 30. The Chinese medicine group (group 1) was treated by promoting ovulation and pregnancy alone; the western medicine group (group 2) was treated with clomiphene citrate (CC) + urinary hgropotin (HMG) + chorionic gonadotropin (HCG) Combination group (group 3) with ovulation Zhu pregnant soup with Western medicine treatment. The ovulation rate, the rate of ovulation, the rate of unlabeled luteinizing syndrome, the incidence of unruptured luteinizing syndrome (LUFS) and the rate of pregnancy within 6 months were compared between the two groups. Results: The ovulation rate in each group was 46.67%, 60.00% and 86.67% respectively, and in group 3 was significantly higher than that in group 1 and 2 (P <0.01). The rate of ovulation was 43.10%, 57.89% and 83.33% The incidence of unruptured luteinizing syndrome was 13.33%, 26.67% and 3.33% in the third group, and lower in the third group than in the first and second groups (P <0.01) (P <0.01). The incidence of unruptured luteinized follicles in each group was 13.79%, 28.07% and 3.70% respectively in the third group, and significantly lower than that in the first and second groups (P <0.01) 20.00%, 40.00% and 63.33% respectively. The third group was significantly higher than the first and second groups (P <0.01). Conclusion: Integrative treatment of anovulatory infertility, the increase in ovulation rate and cycle ovulation rate, reduce the incidence of follicular unruptured luteinized syndrome and periodic follicular unruptured luteinized syndrome and increase the rate of pregnancy within 6 months , Has a unique effect. The simple Chinese medicine to promote ovulation slow, simple Western medicine treatment of follicular unruptured luteinizing syndrome and periodic follicular uncracked luteinized syndrome.