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目的：观察中药淫羊藿对维持性血液透析（ＭＨＤ）患者Ｔ淋巴细胞亚群的影响。方法：将２０例ＭＨＤ患者随机分成２组，采用相同的ＭＨＤ方式（每周３次，每次４小时）。治疗组同时每日给予淫羊藿１５ｇ，煎液２０～３０ｍｌ，分２次口服。２组分别于透析第１、５、９、１３和２５周的第１次透析前作外周血Ｔ淋巴细胞亚群ＣＤ＋４、ＣＤ＋８检测。结果：治疗组９周后Ｔ淋巴细胞ＣＤ＋４较对照组均明显增高（Ｐ均＜０．０５），ＣＤ＋４／ＣＤ＋８比值均较对照组增高（Ｐ均＜０．０５）；治疗组在２５周内各种感染机会较对照组明显减少（Ｐ＜０．０５）。结论：淫羊藿能改善ＭＨＤ患者细胞免疫功能，增加Ｔ淋巴辅助细胞，增强抗感染能力
OBJECTIVE: To observe the effect of herb Epimedium on T lymphocyte subsets in maintenance hemodialysis (MHD) patients. METHODS: Twenty patients with MHD were randomized into 2 groups using the same MHD method (3 times per week, 4 hours each time). The treatment group was given epimedium 15g daily, decoction 20 ~ 30ml, 2 times orally. In the two groups, peripheral blood T-lymphocyte subsets CD+4 and CD+8 were detected before the first dialysis at weeks 1, 5, 9, 13 and 25, respectively. Results: After treatment for 9 weeks, the CD4+ levels of T lymphocytes in the treatment group were significantly higher than those in the control group (P<0.05). The ratio of CD+4/CD+8 was higher than that in the control group (P<0.05). The treatment group was within 25 weeks. The chance of various infections was significantly lower than that of the control group (P<0.05). Conclusion: Epimedium can improve the cellular immune function of patients with MHD, increase T-lymphoid helper cells, and enhance anti-infective ability