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本文报道了1例经病理确诊为恶性组织细胞增生症患者。患者就诊后1个月内开始用COP方案(环磷酰胺、长春新碱、强的松)化疗。化疗后病情显著好转。COP化疗6个疗程,临床缓解3个多月。后来在继续化疗中病情复发,用COP加依托珀甙无显效。患者持续高热,用小剂量萘普生降高热,碳酸锂、免疫调节剂、抗感染、中药等综合治疗,后又用COP
This article reported a case of patients diagnosed with malignant histiocytosis by pathology. Within 1 month of the patient’s visit, chemotherapy with the COP regimen (cyclophosphamide, vincristine, prednisone) was started. The condition improved significantly after chemotherapy. COP chemotherapy for 6 courses, clinical remission for more than 3 months. Later, the condition recurred during continued chemotherapy, and there was no marked effect with COP plus Topotepa. The patient continued to have high fever, treated with low-dose naproxen, fever, lithium carbonate, immunomodulators, anti-infectives, Chinese medicine, etc., and then used COP.