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目的观察玉屏风口服液联合沙美特罗替卡松气雾剂治疗小儿哮喘的临床疗效。方法选取2012年6月至2014年6月在我院就诊的74例哮喘患儿作为研究对象,按照随机数字表法分为治疗组和对照组。对照组吸入沙美特罗替卡松气雾剂,治疗组给予玉屏风口服液联合沙美特罗替卡松气雾剂,观察哮喘的复发和控制情况。结果与同组治疗前比较,患儿肺功能指标均明显改善(P<0.05);治疗组治疗后和停药6月后与对照组比较,患儿肺功能改善显著(P<0.05)。治疗组在治疗后以及停药6月后,有效控制率高于对照组,复发率低于对照组,差异有统计意义(P<0.05)。结论沙美特罗替卡松气雾剂联合玉屏风口服液治疗小儿哮喘的疗效较单用沙美特罗替卡松气雾剂治疗效果更好,且复发率低。
Objective To observe the clinical efficacy of Yupingfeng oral liquid combined with salmeterol and fluticasone aerosol in the treatment of pediatric asthma. Methods Totally 74 children with asthma who were treated in our hospital from June 2012 to June 2014 were selected as study subjects and divided into treatment group and control group according to random number table. The control group inhaled salmeterol and fluticasone aerosol, and the treatment group was treated with Yupingfeng oral liquid combined with salmeterol and fluticasone aerosol to observe the relapse and control of asthma. Results Compared with the same group before treatment, the indexes of pulmonary function in children were significantly improved (P <0.05). Compared with the control group, the lung function of children in treatment group and control group were significantly improved after treatment (P <0.05). The effective rate of control group after treatment and after stopping drug administration for 6 months in treatment group was lower than that in control group, with a statistically significant difference (P <0.05). Conclusion The effect of salmeterol and fluticasone aerosol combined with Yupingfeng oral liquid in the treatment of pediatric asthma is better than that of salmeterol and fluticasone alone aerosol, and the recurrence rate is low.