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目的:比较分析不同剂量奥美拉唑治疗非静脉曲张上消化道出血的临床治疗效果。方法:选取我院的62例非静脉曲张上消化道出血的患者,随机将其分为实验组与对照组。使用大剂量奥美拉唑治疗实验组患者,采用临床常规用量的奥美拉唑治疗对照组患者,比较两种方法的临床治疗效果以及发生不良反应的情况。结果:实验组的总有效率为(87.09%)远远大于对照组的(61.29%),具有统计学意义(p<0.05)。实验组患者的不良反应的发生率为(9.68%)与对照组的不良反应发生率(16.14%)差异无统计学意义(p>0.05)。结论:使用大剂量奥美拉唑治疗非静脉曲张上消化道出血效果显著,不良反应发生率低,建议广泛推广运用。
Objective: To compare the clinical effects of different doses of omeprazole in the treatment of non-varices upper gastrointestinal bleeding. Methods: 62 cases of non-variceal upper gastrointestinal bleeding in our hospital were randomly divided into experimental group and control group. The use of high-dose omeprazole treatment of patients in the experimental group, the use of conventional omeprazole clinical control patients in the control group, comparing the clinical efficacy of the two methods and the occurrence of adverse reactions. Results: The total effective rate (87.09%) in the experimental group was significantly higher than that in the control group (61.29%), with statistical significance (p <0.05). The incidence of adverse reactions in the experimental group (9.68%) was not significantly different from that in the control group (16.14%) (p> 0.05). Conclusion: The use of high-dose omeprazole treatment of non-varices upper gastrointestinal bleeding effect is significant, the incidence of adverse reactions is low, it is recommended to promote the use of a wide range.