目的;探讨米索前列醇用于足月引产的效果。方法:对152例足月单胎头位初产妇,用米索前列醇放置于阴道后穹窿引产和催产素静脉点滴对照组比较。结果:诱发规律宫缩时间,米索组优于催产素组。两组比较有显著差异。剖宫产率低于催产素组,两组比较有显著性差异。产后出血率及新生儿窒息率,新生儿出生体重并无差异。结论:米索前列醇用于足月引产,缩短发动规律宫缩时间,降低剖宫产率,安全有效,值得进一步探讨。 Objectives; To explore the effect of misoprostol for term labor. Methods: 152 cases of full-term single-head primipara, misoprostol placed in vaginal fornix and oxytocin intravenous drip comparison group. Results: Induced regular contractions time, misoprostol group than oxytocin group. There were significant differences between the two groups. Cesarean section rate was lower than oxytocin group, there was significant difference between the two groups. Postpartum hemorrhage rate and neonatal asphyxia, neonatal birth weight and no difference. Conclusion: Misoprostol is used for full-term induction of labor, which shortens the time of onset of contractions and reduces the rate of cesarean section, which is safe and effective. It is worth further study.