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目的:探讨糖尿病患者尿微量白蛋白(mALB)排泄量与糖尿病病程、血糖水平的相互关系。方法:尿蛋白阳性的糖尿病患者按病程、血糖水平分组,采用免疫比浊法测定其尿mALB含量,并与对照组进行比较。结果:对照组mALB含量为11.16±4.28μg/mL,尿蛋白阳性的糖尿病患者尿mALB含量为14.46±5.09μg/mL,两者有显著差异。糖尿病患者随着病程延长,mALB明显升高,与病程短者相比有显著性差异。mALB随血糖升高而增加,有显著性差异。结论:对糖尿病患者要及早诊断,有效控制血糖,还要防止长期服药对肾脏的毒性作用,以延缓糖尿病肾病的发生。
Objective: To investigate the relationship between urinary albumin (mALB) excretion and duration of diabetes and blood glucose level in patients with diabetes mellitus. Methods: Urine protein-positive diabetic patients were divided into groups according to the course of disease and blood glucose level, and their urinary mALB levels were measured by immunoturbidimetry and compared with the control group. Results: The mALB content in the control group was 11.16 ± 4.28 μg / mL, while the urine mALB content in the urine protein positive patients was 14.46 ± 5.09 μg / mL. There was significant difference between the two groups. Diabetic patients with longer duration, mALB was significantly increased, compared with the shorter duration of a significant difference. mALB increased with the increase of blood sugar, there was a significant difference. Conclusion: Diabetes patients should be diagnosed as early as possible to effectively control blood sugar, but also to prevent the toxic effects of long-term medication on the kidney in order to delay the occurrence of diabetic nephropathy.