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对孕期妇女心血管系统发生的变化已有许多很好的描述,包括心输出量、血容量显著增加和外周血管阻力明显减小。自主神经系统对外周血管阻力有明显影响,因其改变了血管的紧张性。孕期该系统对维持血压和子宫血液灌注是一重要因素。血管对肾上腺素能刺激的反应是自主调节的主要方面之一。本研究目的是验证下述假设:大鼠肠系膜血管阻力在孕期对肾上腺素能的刺激反应下降。实验采用孕早期(7～9天)和孕晚期(19～20天)大鼠的肠系膜动脉将其游离并连接在特殊设
There are many well-described descriptions of changes in the cardiovascular system in women during pregnancy, including cardiac output, a significant increase in blood volume, and a significant reduction in peripheral vascular resistance. Autonomic nervous system has a significant impact on peripheral vascular resistance, because it changes the vascular tension. This system during pregnancy is an important factor in maintaining blood pressure and uterine blood perfusion. The vascular response to adrenergic stimulation is one of the major aspects of autonomic regulation. The purpose of this study was to verify the hypothesis that rat mesenteric vascular resistance decreased adrenergic stimulation during pregnancy. Experimental use of early pregnancy (7 to 9 days) and third trimester (19 to 20 days) rat mesenteric artery free and connected to a special set