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目的:观察细菌感染患者抗感染辅助降低血黏度治疗的CRP(C反应蛋白)及血液流变学指标变化,探讨辅助降低血黏度治疗临床价值。方法:挑选80例细菌感染患者随机盲法对照试验分2组,对照组只用抗生素,治疗组加用银杏达莫30mL加0.9%生理盐水250mL静脉注射,每天1次,或口服复方丹参片3片,每天3次。观察临床指标、细菌学和临床疗效。结果:入院时及入院第3、5天,治疗组CRP、血浆黏度、白细胞总数、中性粒比值分别为(26.0±1.6)、(1.89±0.35)、(18.99±1.7)、(0.9±1.6),(22.2±2.0)、(4.43±0.34)、(11.39±1.6)、(0.65±0.06),(7.68±0.9)、(1.33±0.09)、(9.71±0.2)、(0.54±0.05);对照组分别为(25.9±1.3)、(1.87±0.36)、(19.90±1.1)、(0.89±0.12),(25.7±1.2)、(1.79±0.33)、(13.32±0.9)、(0.77±0.09),(10.13±1.1)、(1.42±0.12)、(10.03±0.5)、(0.60±0.09)。2组比较,P<0.05。结论:对细菌感染患者抗感染同时辅助降低血黏度治疗有一定临床价值。
Objective: To observe the changes of CRP (C-reactive protein) and hemorheology indexes in patients with bacterial infection, which are anti-infection and help to reduce blood viscosity, and to explore the clinical value of reducing blood viscosity. Methods: Eighty patients with bacterial infection were randomly divided into two groups. Patients in the control group were treated with antibiotics alone. The patients in the control group were given ginkgolduma 30 mL plus 0.9% normal saline 250 mL intravenously once a day or orally with compound Danshen tablets 3 3 times a day Clinical indicators, bacteriological and clinical efficacy were observed. Results: The CRP, plasma viscosity, white blood cell count and neutrophil ratio in the treatment group were (26.0 ± 1.6), (1.89 ± 0.35), (18.99 ± 1.7) and (0.9 ± 1.6 (22.2 ± 2.0), (4.43 ± 0.34), (11.39 ± 1.6), (0.65 ± 0.06), (7.68 ± 0.9), (1.33 ± 0.09), (9.71 ± 0.2), (0.54 ± 0.05) (25.9 ± 1.3), (1.87 ± 0.36), (19.90 ± 1.1), (0.89 ± 0.12), (25.7 ± 1.2), (1.79 ± 0.33), (13.32 ± 0.9), (0.77 ± 0.09 ), (10.13 ± 1.1), (1.42 ± 0.12), (10.03 ± 0.5), (0.60 ± 0.09) respectively. 2 groups, P <0.05. Conclusion: Infection of patients with bacterial infection while helping to reduce blood viscosity treatment has some clinical value.