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尿蛋白电泳和血浆蛋白肾清除率的测定结果,对于肾脏疾病的诊断及预测激素等药物的疗效,均有一定的临床意义。本文采用蛋白质纸上电泳的方法,测定102例(265例次)成人慢性肾炎患者的尿清蛋白/γ球蛋白(下简称a/γ)比值与γ球蛋白清除率/清蛋白清除率(下简称Cγ/Ca)比值;分析了尿a/γ比值、Cγ/Ca比值和肾功能试验——内生肌酐清除率(C_(ογ)三者之间的关系。结果提示患者在肾功能受到损害时,尿a/γ比值明显降低,而Cγ/Ca比值明显增高。
Urine protein electrophoresis and plasma protein renal clearance results, for the diagnosis of renal disease and predict the efficacy of drugs such as hormones, have some clinical significance. In this study, proteinuric paper electrophoresis method was used to determine the ratio of urinary albumin / γ-globulin (a / γ) and γ-globulin clearance / albumin clearance in 102 patients with chronic glomerulonephritis (265 cases) (Cγ / Ca ratio), and analyzed the relationship between urinary a / γ ratio, Cγ / Ca ratio and renal function test-endogenous creatinine clearance (C_ (ογ)) .The results suggest that patients with impaired renal function Urinary a / γ ratio decreased significantly, while Cγ / Ca ratio increased significantly.