基因免疫是近年发展起来的一种免疫策略。它是指将编码外源蛋白的基因表达载体直接导入机体以激发机体产生特异性免疫应答。自１９９２年Ｔａｎｇ等率先报道以此法在小鼠体内获得成功以来〔１〕，针对流感等疾病的基因免疫研究大量涌现。１９９３年以后Ｄａｖｉｓ等多位学者开 Gene immunization is an immunization strategy developed in recent years. It refers to the gene encoding foreign gene expression vector into the body directly to stimulate the body to produce a specific immune response. Since 1992, Tang and other first reported this method in mice since the success of 〔1〕, for the flu and other diseases of gene vaccination has emerged in large numbers. After 1993, many scholars such as Davis opened