论文部分内容阅读
目的分析深圳市放射工作人员的职业健康损害情况,为评价放射卫生防护工作提供依据。方法对该市2008—2011年4年间接受放射卫生监护健康检查的825名放射工作人员进行周围血淋巴细胞染色体畸变检测。比较不同年份、不同工龄、不同性别、不同工种类放射工作人员周围血淋巴细胞染色体畸变类型情况。结果 2008—2011年放射工作人员染色体畸变率分别与对照组人员比较,差异均有统计学意义(P<0.05﹚;染色体畸变率按不同年份由高到低为2008、2009、2011和2010年;男女变化情况差异无统计学意义(P>0.05);不同放射接触工龄组随着工龄增加而升高,其中>30 a工龄放射工作人员比<10、10～19、20～29 a工龄明显增高,差异有统计学意义(P<0.05)。工业射线组放射工作人员染色体畸变检出率高于医务射线组,且两者都高于对照组,差异有统计学意义(P<0.05);无着丝粒畸变细胞(断片、微小体、无着丝粒环)高于双着丝粒(dic)和环状染色体(r)发生率。结论长期职业性接触低剂量电离辐射可使放射工作人员周围血淋巴细胞染色体畸变率升高,应加强放射工作人员的防护,减少电离辐射损伤效应。
Objective To analyze the occupational health damage of radiation workers in Shenzhen and provide the basis for evaluating radiation health protection. Methods Totally 825 radiation workers who underwent radiological health monitoring in the city from 2008 to 2011 were tested for chromosomal aberrations of peripheral blood lymphocytes. To compare the types of chromosomal aberrations in peripheral blood lymphocytes around radiographers of different years, ages, genders and types of workers. Results The chromosome aberration rates of radiographers from 2008 to 2011 were respectively compared with those of the control group (P <0.05). The chromosome aberration rate was from high to low in different years 2008, 2009, 2011 and 2010; There was no significant difference between men and women (P> 0.05). The working age group with different radiation exposure increased with the increase of seniority, and the working age of staff> 30 years old was significantly higher than that of <10,10-19 and 20-29 years , The difference was statistically significant (P <0.05). The detection rate of chromosome aberration in industrial radiography workers was higher than that in medical radiology group, and both of them were higher than that of control group (P <0.05). There were no aberrant cells (fragments, microsomes, Centromere ring) is higher than the incidence of dicentric (dic) and circular chromosome (r). Conclusion Long-term occupational exposure to low-dose ionizing radiation can increase the chromosome aberration rate of peripheral blood lymphocytes in radiation workers. Radiation workers should be strengthened to reduce the damage effect of ionizing radiation.