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有人认为,HIV-1感染者发生与应用核苷类逆转录酶抑制剂(NRTIs)有关的一些副作用,其共同原因是线粒体产能能力降低。目前已知一种以乳酸酸中毒和肝脂肪变为特征的综合征是应用NRTIs的罕见并发症,某些死亡原因被归委于此。Fouty等在研究NR-
It has been suggested that HIV-1 infected patients have some of the side effects associated with the use of nucleoside reverse transcriptase inhibitors (NRTIs), a common cause of which is their diminished capacity for mitochondrial production. It is now known that a syndrome characterized by lactic acidosis and hepatic steatosis is a rare complication of the use of NRTIs and that some of the causes of death are assigned here. Fouty et al in the study of NR-